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Chirality

Chirality
Contributors
Dalila Kovacs
Grand Valley State University
Beyond Benign
Beyond Benign, Inc.
Learning Objets
Summary
The stereochemistry of a molecule can have a drastic impact on its efficacy and toxicity. This activity provides instructors with homework and discussion questions for use within organic chemistry courses to discuss the importance of understanding the toxicity of stereoisomers using common pharmaceuticals and drugs.
Keyword Tags
Toxicology
Chirality
Stereochemistry
Toxicodynamics
Toxicokinetics
File (PDF, PPT, image, etc)
chirality_nov2025.docx
Learning Goals/Student Objectives
- Identify stereocenters in commonly studied active pharmaceutical ingredients (APIs)
- Understand how structural properties affect water solubility and spectroscopic signals
- Understand the difference between toxicodynamics and toxicokinetics
Object Type
Activities/Technology (e.g., in-class activities, online games, hands-on activities/manipulatives, outreach, virtual tools, etc.)
Other
Audience
Introductory Undergraduate
Green Chemistry Principles
Designing Safer Chemicals
U.N. Sustainable Development Goals (SDGs)
Good Health and Well-Being
Safety Precautions, Hazards, and Risk Assessment
N/A

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Submitted by

Tyler Schisler
Published on
Moderation state
Published
Creative Commons License
Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.