Toxicology for Chemists Curriculum

This module serves as a good first introduction to toxicology. In the first part of the module, students will learn and understand: the history of toxicology and its underlying principles; the progression of toxicology as a science; the development of regulatory agencies; key case studies that developed the field; and the paradox of uncertainty. In the second part of the module, students will ...

This module is an introduction to understanding the principles of hazard and risk. The lectures are designed with a “choose your own adventure” format: you can take any slides and use them in any order to build your lecture! Using these materials, students will understand the basic concepts of hazard, exposure, and risk; be able to perform a simple chemical hazard assessment; be able to compare ...

This module is an introduction to toxicokinetics and toxicodynamics. The module is split into five lectures addressing: absorption, distribution, biotransformation, excretion, and toxicodynamics. Using these materials, students will be able to: explain and describe ADME; learn introductory biochemistry, chemistry, and anatomy to explain ADME; and explain and describe toxicodynamics. The lecture ...

This module gives an overview of the main reaction mechanisms seen in toxicology studies. Students will learn primarily about the main electrophilic reactions that bind toxicants to proteins, in addition to a brief introduction to reactive oxygen species and radical reactions. This module pairs well with Module 11 – Structure-Activity Relationships, and these lecture slides are also included for ...

This module is a good introduction to metal toxicity. Students will learn about the toxicity of metals in the body, metal pollution, the difference between metals and metalloids, mechanisms of heavy metal toxicity, and factors that affect metal toxicity. These lecture slides are heavily case-study based and provide an applied outlook on the chemistry with reference to many global incidents and ...

This module contains an introduction to the concepts of fate, persistence, and biodegradation. Students will learn about: classes of molecules that persist in the environment; different types of degradation and their critical role in the environment and society; and parameters that affect biodegradation rate. Part II of this module is a full case study entirely based on the Deepwater Horizon oil ...

This module serves as an introduction to the principles of environmental toxicity: air pollution, water pollution, and chemical transport and fate. Using these materials, students will learn examples of pollutants and their effects on human health and the environment through multiple case studies and in-class discussions. These lecture slides comprise mostly case studies and provide a good outlook ...

This module provides an introduction to ecotoxicology, an overview of exposure and thresholds, an overview of the main concepts and scales of ecotoxicology, and some applications of ecotoxicology. Using these materials, students will learn: the history of ecotoxicology; why ecotoxicology is important to sustainability; effects on levels of biological organization; relations to hazard and risk ...

This module provides an overview of computational methods to predict the toxicity of chemicals. Students will learn an updated overview of the latest methods that have been successfully applied to predict toxic effects of chemicals, in addition to understanding the outlook towards at the nexus of computational sciences and toxicology. Particular emphasis is placed on carbon-based toxicants ...

This module connects the structure of molecules to their activity in biological systems. Students will be able to: identify physicochemical properties related to ADME; identify and rationalize relationships between physiochemical properties and biological activity in different species; apply pre-screening tools for acute and chronic human and ecological endpoints based on physicochemical ...

Don’t have much time to prepare your lectures? Don’t know where to start with incorporating toxicology into existing class lectures or assignments? Not sure if you’re ready to adopt a full module? Do you just want access to the case studies, in-class assignments, homework assignments, and ChemToxTidbits slides? This folder contains all of these materials in a format easily accessible to you so ...